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Self-Assessment Modules

ID
Test Name
StatusAction
25 FGFR1 mutations in Rosette-forming glioneuronal tumors of the fourth ventricle
The educational design of this activity addresses the needs of physicians and scientist in the field of neuropathology and surgical pathology involved in the diagnosis and/or treatment of patients with brain tumors.

After completing this activity, participants should be better able to:
  1. Compare molecular genetic characteristics of rosette-forming glioneuronal tumors (RGNT) and pilocytic astrocytomas.
  2. Estimate the frequency of FGFR1 mutations in RGNT as suggested by the paper.
  3. Discuss clinical and histological correlations of FGFR1 mutations in RGNT.

Available
(attempts allowed: 3)
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26 CDKN2A Loss Is Associated With Shortened Overall Survival in Lower-Grade (World Health Organization Grades II-III) Astrocytomas
The educational design of this activity addresses the needs of physicians and scientists in the field of neuropathology and neurology involved in the research and prognosis of WHO grade II and III astrocytomas, as well as the diagnosis and/or treatment of patients with cancerous brain tumors.

After completing this activity, participants should be better able to:
  1. Illustrate the basic mechanism of CDKN2A gene.
  2. Express the significance of CDKN2A in astrocytic tumors and oligodendroglial tumors.
  3. Discuss significance of CDKN2A mutations and its relation with other mutations including IDH1, IDH2, ATRX, and p53 from the perspective of patient survival. 

Available
(attempts allowed: 3)
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36 Leigh Syndrome: Neuropathology and Pathogensesis
The educational design of this activity addresses the needs of physicians and scientists in the field of neuropathology and neurology involved in the research, diagnosis, and prognosis of metabolic disorders affecting the central nervous system.

After completing this activity, participants should be better able to:
  1. Explain clinical and radiologic correlations in Leigh syndrome.
  2. Summarize the molecular genetic characteristics of Leigh Syndrome. 
  3. Discuss application of the Ndufs4 mouse animal model and hypoxia model findings to clinical practice.

Available
(attempts allowed: 3)
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